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br Methods br Results A total of patients males
2018-10-23
Methods Results A total of 102 patients (69 males and 33 females, 70.1±9.2years) were registered in the study. Baseline clinical characteristics are presented in Table 1. Telomere G-tail length was negatively correlated with aging and positively correlated with total telomere length (ρ −0.287,
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This study demonstrates the current and important
2018-10-23
This study demonstrates the current and important trend of incorporating a multidimensional approach to assessing interactive illness risk and progression processes in youth at confirmed high-risk (). However, the interpretation of the specific findings should be taken as preliminary given several l
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br Discussion Standard protocols of the assessment of neurop
2018-10-23
Discussion Standard protocols of the assessment of neuropathic pain have been widely agreed for specialist settings and primary care (Haanpää et al., 2011; Jones & Backonja, 2013). However, there is no common approach or consensus reached by clinicians or researchers to define neuropathic pain in
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We also identified a peak in the Chr p next
2018-10-23
We also identified a peak in the Chr8p23.1 next to HMGB1P46 when analysing the male only dataset, and the P value of the top SNP rs6986153 was 8.02×10 with an OR of 1.67. HMGB1P46 is a pseudogene of high mobility group box-1 (HMGB1). It is suggested that the induction of high mobility group box-1 in
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We previously identified JACIE accreditation as a center
2018-10-23
We previously identified JACIE accreditation as a center-specific factor after allogeneic HSCT and found indications for an effect of patient volume (Gratwohl et al. 2014). We used this aa-dutp well-defined large cohort of patients to investigate the multifaceted relationship between potential cent
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The dose response relationships between alcohol and chronic
2018-10-23
The dose–response relationships between alcohol and chronic disease typically vary by sex, with women experiencing higher risks at comparatively lower levels of intake (Shield et al., 2013) due to different grams to moles calculator and metabolism of alcohol (Mumenthaler et al., 1999). New studies
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br Skin and Hair Aging Lifestyle and the
2018-10-23
Skin and Hair Aging, Lifestyle and the Skin and Scalp Microbiomes William W. Mohn (Vancouver, Canada) reported on a cross-sectional study investigating the skin and scalp microbiome in relation to skin and hair aging and lifestyle, and involving 495 subjects 10–78years of age. Diversity of the sc
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In this issue of Vranckx and colleagues
2018-10-23
In this issue of , Vranckx and colleagues show that a LEDGIN termed CX014442 specifically alters HIV-1 genomic integration in a manner that is similar to that associated with LEDGF depletion (). The authors carefully characterized HIV integration sites in the presence of various concentrations of CX
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br Methods br Discussion We systematically searched the
2018-10-23
Methods Discussion We systematically searched the literature from the last five years to identify potential blood biomarkers for cancer (Hanahan & Weinberg, 2011; Cree, 2011). The data mining process retrieved 3990 citations from the initial 19, 724 records, screening the abstracts of these ci
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Although de novo hepatic lipogenesis contribute to liver FFA
2018-10-23
Although de novo hepatic lipogenesis contribute to liver FFA abundance, circulating FFA represent greater pools for hepatic FFA accumulation. Under physiologic conditions, intrahepatic FFA can be re-esterified and stored as TG in lipid droplets (Neuschwander-Tetri, 2010). Recent studies demonstrated
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br Materials and Methods br Ethics Statement
2018-10-23
Materials and Methods Ethics Statement Results Discussion Clinical interest in PARP-1 has increased over the past decade with the recognition of its roles in transcription regulation, DNA repair, epigenetic bookmarking, and selective serotonin reuptake inhibitors restructuring. Currentl
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Importantly Marro et al used a viral mouse model to
2018-10-23
Importantly, Marro et al. used a viral mouse model to demonstrate that progression to T1D can be directly modulated through IFN-α signaling. In their model, Rip-LCMV, C57Bl/6 mice expressed a transgene of the lymphocytic choriomeningitis virus (LCMV) glycoprotein under the control of the rat insulin
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For each of the rHSA samples approximately g were
2018-10-23
For each of the rHSA samples, approximately 10µg were diluted in 50mM ammonium bicarbonate to a total volume of 200µl. To each solution 10µl of 250mM dithiothreitol (DTT) in 50mM NH4HCO3 were added followed by incubation for 1h at 60°C. Next, 20µl of 250mM iodoacetamide in 50mM NH4HCO3 were added an
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br Data The data being shared describe the mechanical and
2018-10-23
Data The data being shared describe the mechanical and structural properties of healing rat myocardial infarcts from individual samples in several post-infarct time points: immediately (i.e. day), 7, 14 and 28 days after the induction of myocardial infarction. The mechanical data are composed of
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br Specifications Table Experimental design materials an htt
2018-10-23
Specifications Table . Experimental design, materials and methods Measurements were taken by a special team of 2 trained assistants, while other information was taken from the RLMS survey which contains questions regarding an individual׳s socioeconomic characteristics and family background [1].