papers about Inhibitor
We aimed here to elucidate whether the effect of taurine increasing proliferation occurs on stem cells as well as on neural progenitor cells. Neurospheres are formed by Phenformin of neural progenitor cells around one or […]
In mice, Oct4 encodes at least 2 variants, designated Oct4A and putative Oct4B. Oct4A was detected in somatic stem cells and has been recognized as a gatekeeper for maintaining pluripotency in embryonic stem cells and […]
Results Discussion We have demonstrated that the hPSC-derived HBCs could be maintained on a human LN111-coated dish in an integrin α6- and β1-dependent manner (Figure 1). It is known that undifferentiated hPSCs could be maintained on […]
Experimental Procedures Human fetal tissues were obtained from Novogenix Laboratories following informed consent and elective termination. Developmental age was determined by ultrasound. Adult articular chondrocytes and synovial membrane were obtained from National Disease Research Interchange. […]
Materials and methods Results Discussion Our findings demonstrate that induced expression of Nkx2.1 in ESCs leads to a significant increase in the generation of Lhx6::GFP+ cINs. The ability to generate specific cell types from ESCs […]
Materials and methods Resource table Resource details This line was derived from a 62-year-old female with familial hypertrophic cardiomyopathy (HCM). HCM is a genetic heart disease with a prevalence of up to 1 in 200 […]
In the current work, we have attempted to address these issues. First, we have successfully generated of iPSCs from USCs, the purchase Tasquinimod that were derived from patients\’ urine, using an integration-free reprogramming protocol. In […]
Introduction Induced pluripotent stem cytoskeleton (iPSCs) are stem cells generated by artificial reprogramming of somatic cells with defined factors, such as Oct4, Sox2, Klf4, and c-Myc (Takahashi and Yamanaka, 2006), which are supplied to target […]
Given the significance of methylation/demethylation during reprogramming, we set out to investigate the function of miR-29a in regulating the iPSC methylome. Although miR-29a was shown to directly regulate both de novo DNA methyltransferases and demethylases, […]
Introduction During their development, Schwann cells (SCs) exist as Schwann cell precursors (SCPs), immature non-myelinating SCs, and mature myelinating SCs (Jessen and Mirsky, 2005). As a major type of glial cell in the peripheral nervous […]